Scientists have discovered genes of regeneration

Scientists have discovered genes of regeneration


As you know, there are on our planet creatures that have an incredible ability to regenerate, allowing you to grow lost limbs and recover the bodies. Many scientists have long argued that virtually any body has the same opportunities — you just “include” the right genes. And recently, German scientists from the max Planck Institute have found such genes.

During their research, University staff researched the larva amphibious animal, ambystoma mexicanum. The fact that she was just a few weeks can completely restore lost limbs. Along with bone, cartilage tissue, muscles, nerves and blood vessels. Moreover, this amphibian can easily cope with fractures of the spine, which for most mammals are deadly.

In the process of studying the larvae of ambystoma mexicanum experts have sequenced their genome and have identified key genes responsible for regeneration of limbs. But this process took a lot of time. The fact that the test genome consists of 32 billion base pairs of DNA (which is about 10 times more than humans). To decode the entire genome, scientists took 72 million reads of DNA, what helped them Analytics platform PacBio, which allows you to sequence in one reading a few hundred thousand fragments. In the course of further analysis of the genome, the researchers found several unique genes that are expressed during regeneration. It is worth noting that at first it was thought that the main of them is the gene PAX3, like other members of the species, but it turned out that РАХ3 generally absent in ambystoma mexicanum, and it is the function of the gene PAX7.

Of course, the “transplantation” of new genes of human speech does not go, and this process requires further study. But now we can use the unique properties to create medicines to heal wounds and to find new ways to repair damaged tissue.